What’s been published/presented?

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Publication Name: British Journal of Cancer (2004) 90, 1120 – 1124
Date: 01-01-2004
Author(s): S Cleator and A Ashworth
Abstract or Overview: Breast cancers are routinely subcategorised on the basis of clinical stage, cellular morphology and immunohistochemical analysis of a small number of markers.

Publication Name: Cancer Res 2005
Date: 01-01-2005
Author(s): Britta Weigelt, Zhiyuan Hu, Xiaping He, Chad Livasy, Lisa A. Carey
Abstract or Overview: Microarray analysis has been shown to improve risk stratification of breast cancer. Breast tumors analyzed by hierarchical clustering of expression patterns of "intrinsic" genes have been reported to subdivide into at least four molecular subtypes that are associated with distinct patient outcomes.

Publication Name: The New England Journal o f Medicine
Date: 01-01-2006
Author(s): Cheng Fan, M.S., Daniel S. Oh, Ph.D., Lodewyk Wessels, Ph.D., Britta Weigelt, Ph.D., Dimitry S.A. Nuyten, M.D., Andrew B. Nobel, Ph.D., Laura J. van’t Veer, Ph.D., and Charles M. Perou, Ph.D.
Abstract or Overview: Gene expression profiling studies of primary breast tumors performed by different laboratories have resulted in the identification of a number of distinct prognostic profiles, or gene sets, with little overlap in terms of gene identity.

Publication Name: Journal of the National Cancer Institute,
Date: 01-01-2006
Author(s): John K. Erban , Joseph Lau
Abstract or Overview: A study published in The Journal of the National Cancer Institute, found that advanced chemotherapy put patients at far greater risks of harm than adverse effect reports from clinical trial data reveal.

Date: 01-01-2006
Abstract or Overview: Background: The number, nature, and costs of serious adverse effects experienced by younger women receiving chemotherapy for breast cancer outside of clinical trials are unknown.


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