Molecular Portraits of Human Breast Tumours

Publication Name: Nature

Author(s): Charles M. Perou, Therese Sùrlie, Michael B. Eisen, Matt van de Rijn, Stefanie S. Jeffreyk, Christian A. Rees

Human breast tumours are diverse in their natural history and in their responsiveness to treatments1. Variation in transcriptional programs accounts for much of the biological diversity of human cells and tumours. In each cell, signal transduction and regulatory systems transduce … Continued