Cost Effectiveness of Gene Expression Profiling for Early Stage Breast Cancer

Publication Name: Cancer

Author(s): Mo Yang, MS; Suja Rajan, PhD; and Amalia M. Issa, PhD, MPH

BACKGROUND: Gene expression profiling (GEP) is being used increasingly for risk stratification to identify women with lymph nodenegative, estrogen receptor-positive, early stage breast cancer who are most likely to benefit from adjuvant chemotherapy. The authors of this report evaluated the … Continued

Head-to-head comparison of the 70-gene signature versus the 21-gene assay: cost-effectiveness and the effect of compliance

Publication Name: Breast Cancer Research and Treatment

Author(s): Valesca P. Retel, Manuela A. Joore, Wim H. van Harten

Both the 70-gene signature and the 21-gene assay are novel prognostic tests used to guide adjuvant chemotherapy decisions in patients with early breast cancer. Although the results of ongoing prospective trials will only become available in some years, the tests … Continued