November 24, 2010
Biological Functions of the Genes in the MammaPrint® Breast Cancer Profile Reflect the Hallmarks of Cancer
Biomarker Insights. 2010 Nov 28;5:129-38. doi: 10.4137/BMI.S6184.
Tian S., Roepman P., Van’t Veer L.J., Bernards R., de Snoo F., Glas A.M.
The study included 3090 clinical low-risk patients with unifocal and 238 patients with multifoGenes in the MammaPrint gene signature comprehensively measure the six hallmarks of cancer-related biology. This finding establishes a link between a molecular signature and the underlying molecular mechanisms of tumor cell progression and metastasis.cal disease.