February 11, 2011

Gene Expression Profiles from Formalin Fixed Paraffin Embedded Breast Cancer Tissue are Largely Comparable to Fresh Frozen Matched Tissue

PUBLICATION: 
PLoS One. 2011 Feb 11;6(2):e17163. doi: 10.1371/journal.pone.0017163.

AUTHORS: 
Mittempergher L., de Ronde J.J., Nieuwland M., Kerkhoven R.M., Simon I., Rutgers E.J., Wessels L.F., Van’t Veer L.J.

SUMMARY: 
We demonstrate that data generated from FFPE material with the DASL assay, if properly processed, are comparable to data extracted from the FF counterpart. Specifically, gene expression profiles for a known set of prognostic genes for a specific disease are highly comparable between two conditions.

Read more: Mittempergher et al_2011_PLoS One_Gene Expression Profiles