January 31, 2002
Gene Expression Profiling Predicts Clinical Outcome of Breast Cancer
Nature. 2002 Jan 31;415(6871):530-6.
van ‘t Veer L.J., Dai H., van de Vijver M.J., He Y.D., Hart A.A., Mao M., Peterse H.L., van der Kooy K., Marton M.J., Witteveen A.T., Schreiber G.J., Kerkhoven R.M., Roberts C., Linsley P.S., Bernards R., Friend S.H.
Development of MammaPrint from 98 tumors, to 78 (non-BRCA). his gene expression profile will outperform all currently used clinical parameters in predicting disease outcome. Our findings provide a strategy to select patients who would benefit from adjuvant therapy.