February 2, 2014

Mammographic Screening Detects Low-Risk Tumor Biology Breast Cancers

PUBLICATION: 
Breast Cancer Res Treat. 2014 Feb;144(1):103-11. doi: 10.1007/s10549-013-2830-5. Epub 2014 Jan 28.7

AUTHORS: 
Drukker C.A., Schmidt M.K., Rutgers E.J., Cardoso F., Kerlikowske K., Esserman L.J., van Leeuwen F.E., Pijnappel R.M., Slaets L., Bogaerts J., Van’t Veer L.J.

SUMMARY: 
Among the screen-detected cancers, 32 % had a 70-gene signature high-risk and 68 % a low-risk tumor, of which 54 % had a ultralow-risk tumor (37 % of total) (Fig. 1a; Table 1). Among the interval cancers, 47 % had a high-risk and 53 % a low-risk tumor, of which 46 % could be defined as ultralow-risk tumor (24 % of total).

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